Table 3.
Meta-analyses of the prognostic value of HSP27 expression in patients with NSCLC
| Survival outcomes | N | No. samples | Heterogeneity (I-squared, p) | Model | HR (95 % CI) | P value | Conclusion | ||
|---|---|---|---|---|---|---|---|---|---|
| Total | PE | NE | |||||||
| 1-year OS | 2 | 140 | 98 | 42 | 91.5 %, 0.001 | Random | 0.885 (0.140–5.599) | 0.896 | Not significant |
| 5-year OS | 3 | 334 | 185 | 149 | 39.6 %, 0.191 | Fixed | 1.832 (1.322–2.538) | <0.001 | Significant |
| 10-year OS | Given up because of the scarcity of included studies | ||||||||
CI confidence interval, HR hazard ratio, HSP27 heat shock protein 27, N reference count, NE negative expression, NSCLC non-small cell lung cancer, OS overall survival, PE positive expression