Table 2.
Regulation trends of apoptosis-related genes in weaning piglets (in vivo) or in the cell model (in vitro)
| Genes | Weaning piglets* | H2O2 model** | X/XO model** |
|---|---|---|---|
| Fas | ↑ | – | ↑ |
| Bcl-2 | ↓ | ↓ | ↓ |
| P53 | ↑ | – | ↑ |
| Caspase 3 | ↑ | ↑ | ↑ |
| Caspase 8 | ↑ | ↑ | ↑ |
| Caspase 9 | – | ↑ | – |
The control groups of in vivo and in vitro test are suckling piglet and PBS treated cell, respectively
* The data for Fas, Bcl-2, Caspase 3, Caspase 8, Caspase 9 are from reference (Zhu et al. 2013), and data for P53 are from reference (Zhu et al. 2012)
** The fold change compared with both reference genes was considered
↑ denotes gene up-regulation, ↓ denotes gene down-regulation, – denotes unchanged gene expression