Table 4.

Histological results at 12 months post-treatment

	ASC	BM-MSC	Chondrocytes
I. Surface	=	+	=
II. Matrix	=	+	+
III. Cell distribution	+	+	+
IV. Cell viability	−	=	=
V. Subchondral bone	=	+	+
VI. Calcification of cartilage	−	−	−
Proteoglycans	−	+	−
Collagen type II	−	−	−

Comparison of the scores that define the quality of the neotissue (according to the ICRS histological grading system) resulting from treatment with three cell sources compared to the controls treated with cell-free scaffolds

ASC adipose-derived MSC, BM-MSCS bone marrow-derived MSC, = same as control, + higher than control, − lower than control