Table 3.
Groups | Pancreas degeneration (maximum score 18) mean ± SD | Edema (maximum score: 3) mean ± SD | Vacuolisation (maximum score: 3) mean ± SD | Necrosis (maximum score: 3) mean ± SD | Fibrosis (maximum score: 3) mean ± SD | İnfiltration (maximum score: 3) mean ± SD | Congestion (maximum score: 3) mean ± SD |
---|---|---|---|---|---|---|---|
Control | 0.25 ± 0.12a | 0.25 ± 0.12a | 0.00 ± 0.00a | 0.00 ± 0.00a | 0.00 ± 0.00a | 0.00 ± 0.00a | 0.00 ± 0.00a |
AP | 8.36 ± 0.52d | 2.84 ± 0.19c | 1.94 ± 0.11d | 1.27 ± 0.14d | 0.63 ± 0.14c | 0.89 ± 0.17c | 0.68 ± 0.13c |
CAR 50 mg/kg | 0.23 ± 0.11a | 0.08 ± 0.02a | 0.02 ± 0.02a | 0.03 ± 0.02a | 0.02 ± 0.01a | 0.03 ± 0.02a | 0.04 ± 0.01a |
CAR 100 mg/kg | 0.16 ± 0.08a | 0.04 ± 0.01a | 0.02 ± 0.01a | 0.03 ± 0.01a | 0.04 ± 0.01a | 0.02 ± 0.01a | 0.02 ± 0.01a |
CAR 200 mg/kg | 0.18 ± 0.06a | 0.08 ± 0.01a | 0.01 ± 0.01a | 0.02 ± 0.01a | 0.01 ± 0.01a | 0.01 ± 0.01a | 0.01 ± 0.01a |
AP + CAR 50 mg/kg | 6.64 ± 0.42c | 2.50 ± 0.10bc | 1.39 ± 0.12c | 1.05 ± 0.08c | 0.38 ± 0.11b | 0.69 ± 0.10b | 0.39 ± 0.11b |
AP + CAR 100 mg/kg | 6.01 ± 0.37c | 2.24 ± 0.12b | 1.22 ± 0.13c | 0.92 ± 0.10c | 0.31 ± 0.14b | 0.61 ± 0.13b | 0.33 ± 0.07b |
AP + CAR 200 mg/kg | 0.74 ± 0.14b | 0.32 ± 0.07a | 0.17 ± 0.02b | 0.13 ± 0.04b | 0.05 ± 0.02a | 0.04 ± 0.02a | 0.03 ± 0.01a |
Data are presented as mean ± SD (n = 7). The means in the same column marked by different letters are significantly different (p < 0.05) from each other. For abbreviations see legend in Table 1