Table 8.
Summary of results
| Cell line | 38 | 47 | 76 | 150 | 160 | 164 |
|---|---|---|---|---|---|---|
| Viability | 35.22 (2) | 30.55 (3) | 28.30 (4) | 26.42 (5) | 39.17 (1) | 25.97 (6) |
| Productivity (total) | 1179.4 (3) | 1462.7 (1) | 1312.5 (2) | 1021.6 (4) | 302.2 (6) | 755.2 (5) |
| Productivity (max) | 386 (3) | 478 (1) | 438 (2) | 344 (4) | 78 (6) | 247 (5) |
| Specific productivity | 4.19 (4) | 5.99 (1) | 5.78 (2) | 4.84 (3) | 0.96 (6) | 3.64 (5) |
| Volume. productivity | 147.4 (3) | 182.8 (1) | 164.7 (2) | 127.7 (4) | 37.8 (6) | 94.4 (5) |
| Productivity efficiency | 33.49 (4) | 47.88 (1) | 46.37 (2) | 38.67 (3) | 7.72 (6) | 29.08 (5) |
| Glucose | 20.93 (2) | 20.41 (1) | 23.25 (6) | 21.36 (3) | 21.37 (4) | 22.34 (5) |
| Lactate | 109.1 (3) | 97.3 (1) | 115.4 (5) | 113.7 (4) | 121.2 (6) | 108.8 (2) |
Cell line—Recombinant CHO-cell line, Viability—VCDx106/ml-8 days, Productivity (total)—Mab, µg/ml-8 days, Productivity (max)—Mab, µg/ml, Specific productivity—Mab μg/cells × 106-day, volumetric productivity (Mab μg/ml/day), Productivity efficiency, CPT/CCT—MAb μg/cells × 106, glucose (mM/ml-8 days), and lactate (mM/ml-8 days)