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. 2016 Jul 26;8:178. doi: 10.3389/fnagi.2016.00178

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Copyright © 2016 Loeffler, Klaver, Coffey, Aasly and LeWitt.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of CSF concentrations of 8-OHdG as a function of age in healthy adults. Age and 8-OHdG were strongly positively associated (ρ = 0.61; p = 0.0001). 8-OHdG levels tended to increase with age with similar patterns for both genders. (dashed lines, men; solid lines, women; 8-OHdG, 8-hydroxy-2′-deoxyguanosine).