Table 3.

Correlations between MIC values, dye staining, and light scattering signals for the imipenem-treated P. aeruginosa strain.

A
AUC	X[MIC]1R2			X[MIC]2R2
sAFH	0.70			0.80
TO-PRO®-3	0.53			0.75
Area FSC/SSC	0.28			0.45
FSC	0.34			0.33
B
Time (h)	AFH X[MIC]2R2	TO-PRO®-3 X[MIC]2R2	FSC/SSC area X[MIC]2R2	FSC X[MIC]2R2
1	0.82	0.8	0.51	0.4
2	0.81	0.70	0.52	0.17
3	0.73	0.68	0.56	0.2
4	0.68	0.69	0.53	0.28

As for E. coli and ampicillin in Table 2, each experiment with P. aeruginosa and imipenem was described by 2 variables: X_[MIC] and Y_[FC], except that two X_[MIC] values were calculated. X_[MIC]1 = 1 if the concentration of imipenem used in the experiment ([Imip]) was ≥ 1 × MIC and X_[MIC]2 = 1 if the [Imip] was ≥ 0.5 × MIC. X_[MIC]1 = −1 if the [Imip] was < 1 × MIC and X_[MIC]2 = −1 if the [Imip] was < 0.5 × MIC. (A) R ²- values calculated between X_[MIC]1 and Y_[FC] (AUC). R²-values calculated between X_[MIC]2 and Y_[FC] (AUC). (B) R²-values calculated between the X_[MIC]2 and Y_[FC] values for each hour of incubation. Two-tailed P < 0.0001.