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. 2016 Apr 23;4:283–295. doi: 10.1007/s40336-016-0172-0

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Induction of hypertrophy after 2 RE-treatments in a patient with CRLM. a CT scan prior to the first treatment with a CRLM located centrally in the right hemiliver, also involving the caudate lobe. b Three months after a whole liver treatment a decrease in the lesion size is seen. Segment 2–3 have hypertrophied (degree of hypertrophy: 16 %). c ⁹⁰Y-PET/CT after a second selective treatment with glass microspheres (8 months after the first RE treatment): an intense accumulation of ⁹⁰Y is seen in the lesion (*). d CT scan 2 months after the second treatment. The lesion in the right hemiliver has further decreased in size. A wedge-shaped hypodense area surrounds the lesion, consistent with radiation changes of the surrounding parenchyma (corresponding to the normal parenchyma with intense ⁹⁰Y uptake on c (*). The hypertrophy of segment 2–3 has increased (degree of hypertrophy: 25 %). Also, segment 4 has hypertrophied (degree of hypertrophy: 20 %)