Fig. 4.

Back pain VAS: adjusted least square mean (SE) change from baseline. Data presented are from MMRM analysis. Model included change from baseline in back pain VAS as dependent variable, visit as a fixed repeated effect and baseline back pain VAS, age, duration of prior bisphosphonate therapy, number of vertebral fractures at baseline, vertebral fractures in the 12 months before starting teriparatide treatment and diagnosis of rheumatoid arthritis or other rheumatological disorder as covariates. *p < 0.0001 compared with baseline. The mean (SD) back pain VAS scores at baseline 3, 6, 12, 18 and 24 months were 50.1 (27.0), 41.0 (25.3), 35.4 (24.3), 31.6 (23.6), 29.7 (23.9), and 27.2 (23.5) mm, respectively