Table 1.
Baseline characteristics of patients in the ExFOS active treatment cohort
| Characteristic | Active treatment cohort (N = 1454) |
|---|---|
| Gender (females, males), n (%) | 1318 (90.6), 136 (9.4) |
| Age (years), mean (SD) | 70.2 (9.8) |
| Body mass index (kg/m2), mean (SD) | 25.6 (4.5) |
| Patients with previous fracture, n (%) | 1239 (85.2) |
| Number of previous fractures, median (Q1, Q3) | 2.0 (1.0, 3.0) |
| Number of previous vertebral fractures, median (Q1, Q3) | 2.0 (1.0, 3.0) |
| Patients with fractures in the 12 months before starting teriparatide, n (%) | 688 (47.3) |
| Patients with vertebral fractures in the 12 months before starting teriparatide, n (%) | 465 (32.0) |
| Patients with maternal history of hip fracture, n (%) | 236 (19.5) |
| Uses arms when standing from chair, n (%) | 756 (52.3) |
| Sight problems, n (%) | 469 (32.5) |
| Current smoker, n (%) | 214 (14.9) |
| Exercises ≥1 h/week, n (%) | 861 (60.1) |
| Hours of exercise/weeka, median (Q1, Q3) | 4.0 (2.0, 7.0) |
| Has at least one alcoholic drink/week, n (%) | 507 (35.7) |
| Number of patients with falls in previous year, n (%) | |
| 1 fall | 287 (20.5) |
| >1 fall | 256 (18.2) |
| Immobilised for >12 months, n (%) | 45 (3.1) |
| Reproductive history for females (n = 1318)b | |
| Reached menopause, n (%) | 986 (98.5) |
| Years since onset of menopause, median (Q1, Q3) | 23.0 (16.0, 29.0) |
| Early menopause (<40 years of age), n (%) | 70 (5.8) |
| Surgical menopause, n (%) | 137 (10.9) |
| Nulliparous, n (%) | 147 (11.2) |
| Prior osteoporosis medication, n (%) | 1289 (88.7) |
| Prior bisphosphonate use, n (%) | 941 (64.7) |
| Duration of prior bisphosphonate therapy (months), mean (SD) | 20.5 (36.6) |
| Current comorbidities, any disease, n (%) | 487 (33.5) |
| Rheumatoid arthritis or other rheumatological disorder, n (%) | 163 (11.2) |
| Taking glucocorticoids, n (%) | 210 (14.4) |
Percentages are based on patients with non-missing data
SD standard deviation, Q1, Q3 first and third quartile of interquartile range
aFor patients who reported exercising
bFifteen women were premenopausal