Table 3.
Clinical and biochemical characteristics of SCH PCOS, euthyroid PCOS, and euthyroid control subjects.
| SCH PCOS (n = 27) (mean ± SD) |
Euthyroid PCOS (n = 68) (mean ± SD) |
Euthyroid control (n = 91) (mean ± SD) |
p value | |
|---|---|---|---|---|
| Age (years) | 29.21 ± 5.9 | 26.37 ± 4.5 | 28.1 ± 3.9 | NSb |
| BMI (Kg/m2) | 32.70 ± 4.9 | 30.91 ± 5.1 | 27.3 ± 4.7 | 0.01a |
| Hypertension n (%) | 7 (25.9) | 11 (16.17) | 5 (5.5) | 0.008a |
| Hirsutism (%) | 25 (92%) | 51 (75%) | 4 (5%) | 0a |
| Ferriman and Gallwey score | 20.91 ± 5.3 | 18.37 ± 4.9 | 8.21 ± 4.3 | 0.1a |
| LH | 13.12 ± 7.6 | 11.39 ± 6.8 | 5.81 ± 3.7 | 0.02a |
| FSH | 4.7 ± 1.9 | 4.8 ± 1.8 | 4.41 ± 1.9 | NSb |
| LH/FSH ratio | 2.9 ± 0.5 | 2.7 ± 0.7 | 1.01 ± 0.29 | NSb |
| Free T3 (pg/mL) | 2.42 ± 1.3 | 2.82 ± 1.3 | 3.73 ± 0.7 | NSb |
| Free T4 (ng/dL) | 1.02 ± 1.0 | 1.23 ± 1.1 | 1.32 ± 1.6 | NSb |
| TSH (mIU/mL) | 7.2 ± 3.5 | 3.1 ± 1.5 | 3.2 ± 1.2 | <0.01a |
| Anti-TPO ab (IU/mL) | 139.54 ± 51.7 | 32.59 ± 5.1 | 19.34 ± 10.3 | <0.001c |
| Free testosterone (pg/mL) | 23.09 ± 6.3 | 18.34 ± 7.9 | 12.2 ± 5.7 | <0.01a |
| Estradiol (pg/mL) | 59.31 ± 18.6 | 63.83 ± 26.7 | 74.24 ± 29.26 | NSb |
| Progesterone (ng/mL) | 2.5 ± 0.6 | 2.9 ± 1.2 | 7.4 ± 4.3 | NSb |
| HOMA-IR | 4.2 ± 1.1 | 2.8 ± 1.4 | 1.8 ± 0.7 | 0.01d |
| Total cholesterol (mg/dL) | 230 ± 29.6 | 198 ± 23.1 | 159 ± 24.8 | 0.01d |
| Triglycerides (mg/dL) | 136 ± 21.3 | 120 ± 16.7 | 84.3 ± 10.6 | 0.001d |
| LDL Chol. (mg/dL) | 151 ± 17.3 | 139 ± 12.6 | 109 ± 20.4 | 0.02d |
| HDL Chol. (mg/dL) | 37.4 ± 15.4 | 45.9 ± 9.6 | 60.3 ± 5.2 | 0.04a |
a p = NS between SCH PCOS and euthyroid PCOS, p < 0.05 between SCH PCOS and euthyroid controls, and p < 0.05 between euthyroid PCOS and euthyroid control group on post hoc analysis.
b p = NS between SCH PCOS and euthyroid PCOS group, p = NS between SCH PCOS and euthyroid controls, and p = NS between euthyroid PCOS and euthyroid control group on post hoc analysis.
c p < 0.05 between SCH PCOS and euthyroid PCOS group, p < 0.05 between SCH PCOS and euthyroid controls, and p = NS between euthyroid PCOS and euthyroid control group on post hoc analysis.
d p < 0.05 between SCH PCOS and euthyroid PCOS group, p < 0.05 between SCH PCOS and euthyroid controls, and p < 0.05 between euthyroid PCOS and euthyroid control group on post hoc analysis.