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Biomarkers and the clinical use in HCC after radiotherapy
| Sample type | No. of patients | Assay | Biomarkers proposed | Comments | References |
|---|---|---|---|---|---|
| Serum | 42 | Enzyme-linked immunoassay | IL-6, SDF-1 | Baseline IL-6, SDF-1 predicted PFS. Decreased SDF-1 at 1-month after RT completion predicted OS. | [48] |
| Blood | 22 | EpCAM mRNA + CTC by qRT-PCR platform | CTC | Decrease in CTC levels after treatment that reflected tumor response. | [49] |
SDF-1=stem cell-derived factor-1; PFS=progression-free survival.
