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. 2016 Jun 30;57(5):1070–1078. doi: 10.3349/ymj.2016.57.5.1070

Table 2. Adverse Events during DTX.

Overall DTX DTX+ADT p value
CTCAE grade ≤2, n (%)
 Thrombocytopenia 1 (2.1) 1 (4.8) 0 (0.0) 0.266
 Anemia 8 (17.0) 3 (14.3) 5 (19.2) 0.657
 Aspartate/alanine aminotransferase increased 14 (29.8) 5 (23.8) 9 (34.6) 0.426
 Nausea & vomiting 29 (61.7) 15 (71.4) 14 (53.8) 0.223
 Diarrhea 9 (19.1) 6 (28.6) 3 (11.5) 0.144
 Constipation 13 (27.7) 8 (38.1) 5 (19.2) 0.155
 Peripheral neuropathy 7 (14.9) 3 (14.3) 4 (15.4) 0.917
 Dry mouth 14 (29.8) 8 (38.1) 6 (23.1) 0.268
 Dry eye 12 (25.5) 7 (33.3) 5 (19.2) 0.275
 Edema limbs 6 (12.8) 2 (9.5) 4 (15.4) 0.554
 Myalgia 11 (23.4) 6 (28.6) 5 (19.2) 0.457
CTCAE grade ≥3, n (%)
 Febrile neutropenia 8 (17.0) 4 (19.0) 4 (15.4) 0.742
 Anemia 1 (2.1) 0 (0.0) 1 (3.8) 0.369
 Nausea & vomiting 2 (4.3) 2 (9.5) 0 (0.0) 0.112
 Peripheral neuropathy 2 (4.3) 0 (0.0) 2 (7.7) 0.199
 Fatigue 2 (4.3) 1 (4.8) 1 (3.8) 0.878

CTCAE, common terminology criteria for adverse events; DTX, docetaxel-based chemotherapy; ADT, androgen deprivation therapy.