Table 1.
Healthy older
|
Mobility-limited older
|
|||
---|---|---|---|---|
N=26 | N=22 | |||
Male | Female | Male | Female | |
N=14 | N=12 | N=10 | N=12a | |
Age (years) | 73.9±3.6 | 74.2±3.9 | 78.5±3.8* | 76.1±4.7‡ |
BMI (kg/m2) | 26.3±3.0 | 24.1±4.4 | 27.2±2.6 | 26.7±4.0 |
MMSE (score) | 29.3±0.8 | 29.2±0.8 | 28.7±1.5 | 28.9±0.9 |
Number of medications | – | – | 3.6±2.5 | 2.1±2.2 |
Number of diagnoses | – | – | 2.7±1.8 | 1.8±1.9 |
Gait speed (m/s) | 1.2±0.3 | 1.2±0.1 | 0.8±0.2* | 0.9±0.1*‡ |
Chair stand (s) | 10.9±2.1 | 12.0±2.4 | 15.7±3.5* | 16.1±4.5*‡ |
SPPB (score) | 11.3±1.2 | 10.8±0.9 | 7.8±1.2* | 7.9±1.4*‡ |
400 m (s) | 292.0±38.1 | 309.4±38.7 | 395.7±57.2* | 364.4±47.5*‡ |
Stair climb (s) | 5.1±0.7 | 5.8±0.7† | 7.6±1.8* | 7.7±2.8‡ |
1RM strength (N) | 1629±200 | 869±211† | 1275±394* | 921±194†‡+ |
Peak power (W) 40 % 1RM | 612±114 | 264±73† | 329±109* | 200(82) †‡+ |
Peak power (W) 70 % 1RM | 656±140 | 256±71† | 358±110* | 230±88†‡+ |
Total muscle CSA (cm2) | 131±13 | 82±10† | 110±14* | 82±21†+ |
Total intermuscular adipose tissue CSA (cm2) | 2.8(1.8) | 2.2±1.6 | 4.8±2.6 | 4.0±1.7*‡ |
Specific strength (N/cm2) | 12.5±1.6 | 10.5±2.2 | 11.5±2.5 | 11.2±1.2+ |
Results are reported as mean±standard deviation or median (interquartile range)
BMI body mass index, MMSE mini-mental state examination, SPPB Short Physical Performance Battery, 40 % 1RM 40 % of a one-repetition maximum, 70 % 1RM 70 % of a one-repetition maximum, 1RM one-repetition maximum, CSA cross-sectional area
p<0.05 (mobility-limited older as compared to healthy older by gender);
p<0.05 (male vs female within group);
p<0.05 (mobility-limited older as compared to healthy older group);
p<0.05 (male vs female)
Only 11 subjects with CT scan available