Table 1. Percentage of inflammatory cells in BALF from different groups of Balb/c mice.
% | control | OVA | 10 μg | 25 μg | |||
---|---|---|---|---|---|---|---|
Eosinophils | 5.25 ± 0.59 | 41.75 ± 2.55 | ** | 35.00 ± 3.55 | ** | 19.00 ± 2.30 | *, ## |
Neutrophils | 9.50 ± 1.21 | 12.25 ± 1.65 | 11.08 ± 1.19 | 10.08 ± 1.25 | |||
Lymphocytes | 15.75 ± 2.47 | 20.83 ± 1.30 | 19.42 ± 1.00 | 13.83 ± 0.77 | # | ||
Macrophages | 69.50 ± 4.03 | 25.17 ± 1.99 | ** | 34.50 ± 2.35 | ** | 57.08 ± 3.66 | ## |
Differential cell counts of four major types of inflammatory cells including eosinophil, neutrophil, lymphocyte and macrophage were obtained, and percentages of each cell type from total cell numbers was calculated for control group (control), OVA-sensitized and challenged group (OVA), and group of OVA-sensitization with BK-1361 treatment at either dose of 10 μg (10 μg) or 25 μg (25 μg) respectively. Data are representative of two independent experiments with n = 5–6 age-matched female mice for each. Results are expressed as mean ± SEM. *P < 0.05, **P < 0.005 versus control. #P < 0.05, ##P < 0.005 versus OVA.