Table 1. Meta-analysis results from survey years 1999–2006 with a threshold of FDR < 1% for systolic blood pressure (SBP).
SBP | Random Effects Meta-Analysis 1999–2006 (training dataset) | |||
---|---|---|---|---|
Variable Name (change per 1 SD of the logarithm of factor) | Effect Size (mmHg) | p-value | Total N | FDR |
Alcohol | 0.04 | 1.4 × 10−11 | 22986 | 2.0 × 10−9 |
Enterolactone | −0.08 | 2.0 × 10−11 | 7850 | 2.2 × 10−9 |
Equol | −0.05 | 1.9 × 10−10 | 7597 | 1.3 × 10−8 |
Mercury, urine | −0.08 | 2.2 × 10−8 | 6986 | 1.3 × 10−6 |
Mono-(3-carboxypropyl) phthalate | −0.05 | 3.1 × 10−6 | 6081 | 0.0001 |
Folate, serum | −0.05 | 4.1 × 10−6 | 22269 | 0.0002 |
2,5-dichlorophenol | −0.06 | 4.4 × 10−6 | 7547 | 0.0002 |
Cadmium, urine | −0.08 | 1.1 × 10−5 | 7457 | 0.0003 |
4-fluoro-3-phenoxybenzoic acid | −0.02 | 1.5 × 10−5 | 3647 | 0.0004 |
Vitamin A | −0.03 | 7.0 × 10−5 | 17829 | 0.002 |
Retinol | −0.03 | 9.0 × 10−5 | 17829 | 0.002 |
Thallium, urine | −0.07 | 0.0002 | 7549 | 0.003 |
Cesium, urine | −0.07 | 0.0003 | 7613 | 0.004 |
Cadmium | 0.03 | 0.0003 | 22493 | 0.005 |
Variables were log transformed and z-standardized therefore results reflect a change per 1 standard deviation (SD). FDR = False Discovery Rate. N = number of participants measured.