Table 3.
PFT Measures | Age, Sex, and Height Adjusted |
Multivariable Adjusted* |
||
---|---|---|---|---|
β Value (SE) | P Value | β Value (SE) | P Value | |
FEV1, % predicted | −1.4 (0.3) | <0.001 | −1.0 (0.3) | 0.001 |
FVC, % predicted | −1.2 (0.3) | <0.001 | −0.7 (0.3) | 0.008 |
FEV1/FVC, % predicted | −0.2 (0.2) | 0.21 | −0.3 (0.2) | 0.07 |
TLC, % predicted | −1.0 (0.5) | 0.04 | −0.7 (0.5) | 0.16 |
DlCO, % predicted | −2.1 (0.4) | <0.001 | −2.2 (0.4) | <0.001 |
Chest CT Measures | OR (95% CI) | P Value | OR (95% CI) | P Value |
---|---|---|---|---|
ILA | 1.57 (1.27–1.94) | <0.001 | 1.59 (1.28–1.97) | <0.001 |
Fibrosis | 1.68 (1.14–2.45) | 0.008 | 1.65 (1.11–2.44) | 0.01 |
Definition of abbreviations: CI = confidence interval; CT = computed tomography; DlCO = diffusing capacity of the lung for carbon monoxide; ILA = interstitial lung abnormality; OR = odds ratio; PFT = pulmonary function test; TLC = total lung capacity.
β-Coefficient and odds ratio are change in pulmonary trait per 1 SD of log-transformed galectin-3.
Adjusted for age, sex, height, body mass index, current or former smoking status, pack-years of smoking, and diabetes.