Table 3.
Correlation between TLR mRNA expression levels and baseline clinical factors (N = 79)
| TLR2 | TLR3 | TLR4 | TLR7 | TLR9 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| R value | P value | R value | P value | R value | P value | R value | P value | R value | P value | |
| HCV RNA | 0.292 | 0.009 | 0.277 | 0.013 | 0.386 | < 0.0001 | 0.301 | 0.007 | 0.354 | 0.001 |
| ALT | −0.126 | 0.269 | 0.046 | 0.688 | −0.009 | 0.934 | 0.097 | 0.393 | −0.05 | 0.663 |
| Cirrhosis | −0.124 | 0.278 | 0.087 | 0.447 | −0.024 | 0.832 | 0.014 | 0.901 | −0.901 | 0.425 |
Spearman correlation. HCV RNA (log IU), ALT alanine aminotransferase (U/dl). Cirrhosis:yes vs. no. TLR mRNA expression levels were shown as log ratios relative to GAPDH mRNA (log 2 -(∆Ct))