Table 2.
Response | Median time to response, days (95 % CI) | p value | ||
---|---|---|---|---|
ETN 50 mg–ETN 25 mg (n = 21) | ETN 25 mg–ACT 10 mg (n = 19) | ACT 10 mg (n = 18) | ||
PASI 75 | 126 (56, 146) | 146 (124, NA) | NA (127, NA) | 0.0448 |
PASI 50 | 56 (28, 56) | 56 (54, 84) | 126 (56, NA) | 0.0033 |
PGA clear/almost-clear | 167 (55, 172) | 165 (59, NA) | NA (87, NA) | 0.3536 |
Abbreviations: ACT acitretin, CI confidence interval, ETN etanercept, NA not available, PASI Psoriasis Area Severity Index, PGA Physician’s Global Assessment