Table 2.
Univariate analysis of factors associated with potential drug-drug interactions
| Characteristic | Frequency % N = 275 |
Number of DDIs Median (Q1-Q3) |
P-value |
|---|---|---|---|
| Gender | |||
| Male | 151 (54.9) | 3 (1–5) | 0.725a |
| Female | 124 (45.1) | 3 (1.25–5) | |
| Age category | |||
| <30 | 40 (14.5) | 2 (1–3) | 0.015b |
| 30–60 | 151 (54.9) | 3 (1–5) | |
| >60 | 84 (30.5) | 3 (2–5) | |
| Smoker | |||
| Yes | 58 (21.1) | 3 (1–5) | 0.834a |
| No | 217 (78.9) | 3 (1–5) | |
| Duration of dialysis (years) | |||
| <4 | 203 (73.8) | 3 (1–5) | 0.920a |
| ≥4 | 72 (26.2) | 3 (2–4) | |
| Total chronic co-morbid disease | |||
| None | 36 (13.1) | 1 (1–3) | <0.001b |
| 1 | 96 (34.9) | 2.5 (1–4) | |
| 2 | 90 (32.7) | 3 (1.75–5) | |
| ≥3 | 53 (19.3) | 4 (2–7) | |
| Total number of medications | |||
| <5 | 26 (9.5) | 1 (0.0–1) | <0.001a |
| ≥5 | 249 (90.5) | 3 (1–5) | |
aMann- Whitney test
bKruscal Wallis test