Skip to main content
. 2016 May 13;152(2):309–322. doi: 10.1093/toxsci/kfw084

TABLE 1.

Summary of Individual and Cumulative PCB 126 Dose, Expressed on a Molar, Weight or TCDD TEQ Basis, for Different Treatment Groupsa

Group Number of Rats PCB 126 Dose/Injection
TCDD TEQb Dose/Injection
Cumulative PCB126 Dose
Cumulative TCDD TEQb Dose
µmol/kg b.w. µg/kg b.w. nmol/kg b.w. µg/kg b.w. µmol/kg b.w. µg/kg b.w. nmol/kg b.w. µg/kg b.w.
Vehicle (corn oil) 10 0 0 0 0 0 0 0 0
Low dose 8 0.01 3.3 1 0.33 0.06 19.8 6 1.98
Medium dose 8 0.05 16.3 5 1.63 0.3 97.8 30 9.78
High dose 8 0.2 65 20 6.5 1.2 390 120 39

aAnimals were acclimatized to the animal facility for 1 week, randomized into the 4 treatment groups, and treated every 2 weeks with i.p. injections of corn oil (vehicle; 5 mL/kg b.w.) or PCB 126 in corn oil (5 mL/kg b.w.) for 3 months.

bThe PCB 126 dose, expressed as TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) toxic equivalent quotient, was calculated using the 2005 WHO TEF of PCB 126 of 0.1 (Van den Berg et al., 2006).