Table 3.
Correlations between clinicopathological findings and the combination of Sema4D and PlexinB1 expresion
| Variables | Sema4D and PlexinB1 expression | p value | |
|---|---|---|---|
| Both positive | Others | ||
| (n = 63) | (n = 163) | ||
| Age (years) | |||
| Mean ± SD | 68.1 ± 10.2 | 66.0 ± 11.7 | 0.351 |
| Gender | |||
| Male | 35 | 89 | 0.897 |
| Female | 28 | 74 | |
| Stage | |||
| I | 7 | 51 | <0.001 |
| II | 11 | 46 | |
| III | 45 | 66 | |
| Histology | |||
| Well/mod | 53 | 149 | 0.123 |
| Other | 10 | 14 | |
| Depth of tumor invasion | |||
| T1/T2 | 10 | 58 | 0.002 |
| T3/T4 | 53 | 105 | |
| Lymph node metastasis | |||
| negative | 18 | 96 | <0.001 |
| positive | 45 | 67 | |
| Lymphatic invasion | |||
| Negative | 9 | 69 | <0.001 |
| Positive | 54 | 94 | |
| Venus invasion | |||
| Negative | 41 | 146 | <0.001 |
| Positive | 22 | 17 | |
Sema4D semaphorin 4D. Other poorly-differnetiated, mucinous-type, small-cell, signet-cell