Table 2.
Changes in vital signs, tissue oxygen metabolism, and myocardial enzymes after the usage of esmolol
| Variables | Before the usage of esmolol (n = 63) | After the usage of esmolol (n = 63) | t | P |
|---|---|---|---|---|
| Systolic blood pressure (mmHg) | 130.5 ± 16.7 | 126.4 ± 18.8 | 1.5 | 0.146 |
| Diastolic blood pressure (mmHg) | 72.8 ± 12.3 | 72.6 ± 12.4 | 0.1 | 0.926 |
| Mean arterial pressure (mmHg) | 90.0 ± 13.8 | 88.7 ± 13.9 | 0.6 | 0.548 |
| Pulse pressure (mmHg) | 57.7 ± 13.3 | 53.8 ± 16.8 | 1.7 | 0.109 |
| Central venous pressure (mmHg) | 6.5 ± 2.1 | 7.5 ± 2.5 | −3.0 | 0.007 |
| Heart rate (beats/min) | 107.8 ± 8.7 | 86.2 ± 10.2 | 20.8 | <0.001 |
| Left ventricular outflow tract cardiac output (L/min) | 5.0 ± 1.8 | 4.3 ± 1.7 | 5.2 | <0.001 |
| Lactate (mmol/L) | 1.4 ± 0.8 | 1.1 ± 0.6 | 2.6 | 0.015 |
| Pcv-a CO2 (mmHg) | 5.6 ± 3.3 | 4.3 ± 2.2 | 2.6 | 0.019 |
| ScvO2 (%) | 78.99 ± 7.95 | 78.06 ± 7.59 | 0.5 | 0.480 |
| Arterial pH | 7.42 ± 0.06 | 7.44 ± 0.06 | −1.3 | 0.192 |
| HCO3− (mmol/L) | 26.4 ± 4.7 | 26.6 ± 4.5 | −0.6 | 0.537 |
| Anion gap correction (mmol/L) | 10.8 ± 4.0 | 10.2 ± 4.4 | 1.0 | 0.362 |
| Urine output (ml/h) | 102.5 ± 88.6 | 106.8 ± 107.7 | −0.3 | 0.760 |
| Peripheral perfusion index | 2.4 ± 1.6 | 2.1 ± 1.4 | 1.8 | 0.079 |
| Creatine kinase (U/L) | 316.1 ± 522.7 | 321.9 ± 580.8 | −0.2 | 0.880 |
| Creatine kinase isoenzyme (ng/ml) | 1.8 ± 2.0 | 2.8 ± 6.1 | −0.9 | 0.403 |
| Troponin I (ng/ml) | 1.5 ± 7.0 | 1.5 ± 7.0 | −0.9 | 0.370 |
| NT-proBNP (pg/ml) | 8825.8 ± 6583.1 | 9313.3 ± 7049.8 | −0.6 | 0.553 |
Pcv-a CO2: Central venous-to-arterial carbon dioxide difference; NT-proBNP: N-terminal pro-brain natriuretic peptide.