Figure 5.

(A) Representative example of consecutive single-channel current traces recorded in the absence and presence of 100 nM OD1. Inward Na⁺ currents were evoked by step depolarization from a holding potential of −100 mV to −20 mV. The beginning of the step is indicated by the arrow and dashed lines correspond to the channel closed state (c). (B) Cumulative distribution of channel open times in control (gray) and the presence of OD1 (red).