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. 2016 Jul 15;57(8):3793–3802. doi: 10.1167/iovs.16-19825

Figure 3.

Figure 3

Overexpression of BDNF prevented the progressive loss of visual acuity for hypertensive eyes. (A) Photos of a control and a BDNF_OE mouse. Right eyes had induced ocular hypertension and left eyes were used as controls. (B) The mean visual acuity of right eyes decreased with time following IOP elevation, while that of the left eyes did not change. BDNF overexpression reduced the progressive loss of visual acuity (bright red line). Sample numbers are given for each data point, and a 2-way ANOVA test was performed (see Results). (C) Scatter plot of visual acuity of left and right eyes of individual mice in the dashed-line box in (B). Dotted line at 0.3 cyc/deg. NS, not significant; ***P < 0.001 in Student's t-test.