Figure 4.
BDNF protected the inner retinal function of mice with chronic ocular hypertension. (A) At 3 months, the mean amplitudes of OPs in OHT eyes had decreased by approximately a factor of 2 in control mice. For BDNF_OE mice (red line), the change was much less dramatic. (B) The mean amplitudes of OPs in control mice continued to decrease with time while it did not change for BDNF_OE mice. n = 5 to 28 mice in each group. *P < 0.05, ***P < 0.001 in 2-way ANOVA, Tukey's posttest.