Figure 5.
Stimulus-locked correlations between the hippocampus and the rest of the brain during Minutes 1–2 of Part 2. (a) ISFC (see Materials and Methods) within each group for the beginning of Part 2 (Minutes 1–2), using the hippocampus as the seed region. Hippocampal activity was significantly correlated with activity in areas with long timescales, including voxels in posterior cingulate, retrosplenial, and medial prefrontal cortex, in the DM group. Hippocampus ROI shown in gray. (b) On average, correlations between the hippocampus and voxels in long-timescale regions were higher in the DM group than those in the NM or RM groups (F3,47 = 5.63, P < 0.005; post hoc t-tests, P < 0.05). (c) Correlations between the hippocampus and voxels in posterior cingulate cortex (PCC) and medial prefrontal cortex (mPFC), 2 regions in the DMN defined from an external atlas, were significantly greater in the DM group compared with the other groups. PCC: F3,47 = 3.70, P < 0.05; t-tests, P < 0.05; mPFC: F3,47 = 4.21, P < 0.05; t-tests, P < 0.05. See also Supplementary Figure 4.
