Table 1.
Characteristics of the sample
| CTR (n = 301) | sMCI-1y (n = 157) | sMCI (n = 110) | lMCIc (n = 71) | eMCIc (n = 87) | AD (n = 282) | F or χ2 (P value) | |
|---|---|---|---|---|---|---|---|
| Age | 75.1 (5.7) | 75.0 (6.5) | 74.7 (7.5) | 74.8 (7.0) | 74.1 (6.7) | 75.6 (7.0) | 0.9 (0.475) |
| Gender (m/f)a,b,c,d,e | 156/145 | 88/69 | 74/36 | 43/28 | 54/33 | 130/152 | 19.2 (0.002) |
| Education (y)f,a,g,h,i,j,k,l,c,m,d,e | 14.2 (4.4) | 11.8 (5.2) | 15.7 (3.0) | 16.1 (3.0) | 13.9 (4.2) | 12.2 (4.9) | 21.2 (<0.001) |
| MMSEf,a,g,n,h,i,b,o,l,c,d,e | 29.1 (1.1) | 27.0 (1.6) | 27.6 (1.7) | 26.7 (1.7) | 26.6 (1.8) | 22.4 (3.5) | 272.8 (<0.001) |
| CDRf,a,g,n,h,b,c,d,e | 0 | 0.5 | 0.5 | 0.5 | 0.5 | 0.9 (0.4) | 880.2 (<0.001) |
Note: Means are followed by standard deviations. Differences in age, years of education, and MMSE scores were assessed using an analysis of variance (ANOVA). Differences in CDR scores were assessed using a Kruskal–Wallis test and differences in gender were assessed using a χ2 test. CTR, controls; sMCI, stable mild cognitive impairment after 1 year (sMCI-1y) or 3 years (sMCI); lMCIc, late mild cognitive impairment converters; eMCIc, early mild cognitive impairment converters; AD, Alzheimer's disease; MMSE, mini-mental state examination; CDR, clinical dementia rating scale.
aSignificant differences between CTR and sMCI patients (P < 0.05).
bSignificant differences between sMCI-1y and AD patients (P < 0.05).
cSignificant differences between sMCI and AD patients (P < 0.05).
dSignificant differences between lMCIc and AD patients (P < 0.05).
eSignificant differences between eMCIc and AD patients (P < 0.05).
fSignificant differences between CTR and sMCI-1y patients (P < 0.05).
gSignificant differences between CTR and lMCIc patients (P < 0.05).
hSignificant differences between CTR and AD patients (P < 0.05).
iSignificant differences between sMCI-1y and sMCI patients (P < 0.05).
jSignificant differences between sMCI-1y and lMCIc patients (P < 0.05).
kSignificant differences between sMCI-1y and eMCIc patients (P < 0.05).
lSignificant differences between sMCI and eMCIc patients (P < 0.05).
mSignificant differences between lMCIc and eMCIc patients (P < 0.05).
nSignificant differences between CTR and eMCIc patients (P < 0.05).
oSignificant differences between sMCI and lMCIc patients (P < 0.05).