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2-Arachidonoyl glycerol reduces IOP in a concentration- and CB1-dependent manner. (A) Shows changes in IOP (mm Hg) after 1 hour, with increasing concentrations of 2-AG lowering IOP in a concentration-dependent manner. (B) Responses to 5 mM 2-AG are absent in CB1−/− animals, but present in CB2−/− animals (C).
