Skip to main content
. 2016 Jun 24;57(7):3369–3379. doi: 10.1167/iovs.16-19291

Figure 5.

Figure 5

Berberine attenuated HOG-LDL–induced Müller cell angiogenesis and inflammation. Müller cells were exposed to HOG-LDL for 24 hours with/without 1 hour pretreatment with berberine (5 μM). (A–C) Angiogenesis related proteins VEGF and PEDF and VEGF:PEDF ratio; (D) proinflammation cytokines iNOS and ICAM-1, detected by Western blot and quantified by densitometry (mean ± SD; n = 3). (E) mRNA levels for IL-6, IL-8, and TNF-α, measured by real-time PCR and expressed as fold change versus control (mean ± SD; n = 3).