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. 2016 Jul 20;5(7):339–351. doi: 10.1002/psp4.12098

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© 2016 The Authors CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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(a) Changes in the phase‐diagram as a function of the bifurcation ratio $β / γ$ . Notice that for $β = γ$ (the bifurcation point), the two steady states of v coalesce into just one steady state v = 1. (b) Bifurcation diagram showing the two steady states of plasma prolactin (PRL) concentration v and their stability as a function of the bifurcation parameter $β / γ$ (MATLAB model code provided in Supplementary Figure S7).