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. 2016 Jul 11;113(29):E4161–E4169. doi: 10.1073/pnas.1605546113

Fig. 1.

Fig. 1.

SSN/GNN analysis of DUF1537 family. (A) SSN for the DUF1537 family (PF07005) displayed at an alignment score of 60 (∼35% sequence identity). The nodes in the network are colored based on conserved genome neighborhoods that encode the members of respective nodes. PdxA2–, aldolase–, and RLP–DUF1537 proteins are denoted by the sea blue, red, and orange nodes, respectively. The UniProt IDs for 22 DUF1537 proteins are also indicated (SI Appendix, Table S1). (B) The cluster-specific GNNs for PdxA2–, aldolase– and RLP–DUF1537 clusters and only the highly conserved [indicated by cluster fraction (CF)], catalytic genome proximal enzyme families specific to these clusters were shown here. (C) Representative PdxA2–DUF1537 and aldolase–DUF1537 gene clusters encoded in R. eutropha H16.