Figure 4.

Structure of Input-Specific Gain Modulation in the Cortex and Thalamus

(A) Example CGF and PRF pairs for four neural recordings in cortex (left) and four recordings in thalamus (right). CGFs (top) range over relative time $\mathit{\tau }$ and relative frequency $\varphi$. Weights represent the change in gain induced if one of the loudest tones of the DRC stimulus were to fall at the corresponding location, and are shown on common scale (left). PRFs (bottom) range over time $\mathit{t}$ prior to the modeled response and acoustic frequency $\mathit{f}$ (log-spaced). Stimulus modulation of firing differs substantially across neurons, so PRFs are separately (and symmetrically) scaled to the maximum change in firing rate shown above each one.

(B–E) Mean CGFs and average profiles in cortex (green) and thalamus (magenta). The central panel (C) shows the spectrotemporal pattern of the mean CGF weights in both structures. The average spectral profiles (B), spectral profiles at 0 delay (D) and average temporal profiles (E) of both means are shown superimposed, with error bars indicating the SE of the estimated population means.