Figure 8.

NBLAST extensions

(A) Larval Drosophila EM tracings. Tanglegrams match two different dendrograms; neurons are plotted by dendrogram group. In the middle, the original neurons; on the left, clustering based on synaptic connectivity network; on the right, NBLAST clustering after pruning first- and second-order terminal branches from neurons. Left tanglegram compares network clustering to NBLAST clustering; right tanglegram compares NBLAST clustering of original and pruned neurons.

(B) Monarch butterfly central complex neurons.

(B′) Neurons after mirroring and clustering colored by dendrogram group. Some brain neuropils are shown in gray.

(B′′) Hierarchical clustering after mirroring neurons.

(C) Zebrafish mitral neurons. Left: hierarchical clustering after mirroring neurons. Right: four examples of pairwise comparisons of neuron groups, colored by dendrogram group.

(D) Vector cloud representation of R43D01 expression pattern (blue) and query FlyCircuit mAL neurons (red).

(D′) R43D01 expression pattern.

(E) Candidate V-glomerulus-selective GAL4 expression pattern with query neuron (VGlut-F-100184).

(F) Identified GAL4 expression patterns found with AMMC-AMMC PN1 auditory neuron (Trh-M-300069) and AOTUv2 lineage neuron (fru-F-200039).