Table 1.

Recent development of new XOR inhibitors reported in the literature.

Compound	Mechanisms	References
9-Benzoyl 9-deazaguanines	Purine analogs	Rodrigues MV et al., 2016 [94]
N-(1,3-Diaryl-3-oxopropyl)amides	Purine analogs	Nepali K et al., 2011 [95]
5,6-Dihydropyrazolo/pyrazolo[1,5-c]quinazoline derivatives	Purine analogs	Kumar D et al., 2014 [96]
Naphthopyrans	Non-purine analogs	Sharma S et al., 2014 [97]
Thiadiazolopyrimidin-5-ones	Non-purine analogs	Sathisha KR et al., 2016 [98]
Aryl-2H-pyrazole derivatives	Non-purine analogs	Sun ZG et al., 2015 [99]
2-Amino-5-alkylidene-thiazol-4-ones	Non-purine analogs	Smelcerovic Z et al., 2015 [100]
2-(Indol-5-yl)thiazoles	Non-purine analogs	Song JU et al., 2015 [101]
1-Hydroxy/methoxy-4-methyl-2-phenyl-1H-imidazole-5-carboxylic acid derivatives	Non-purine analogs	Chen S et al., 2015 [102]
Riparsaponin	Natural substance	Xu F et al., 2014 [103]
Genistein (4′,5,7-Trihydroxyisoflavone)	Natural substance	Lin S et al., 2015 [104]
Morin	Natural substance	Zhang J et al., 2016 [105]
Curcumin analogs	Natural derivatives	Shen L et al., 2009 [106]
Oxidation product of caffeic acid	Natural derivatives	Masuda T et al., 2014 [107]
Aloe-emodin derivatives	Natural derivatives	Shi DH et al., 2014 [108]
DHNB (3,4-Dihydroxy-5-nitrobenzaldehyde)	Natural derivatives	Lü JM et al., 2013 [109]