Fig. 1.

Changes in forced vital capacity (FVC) in the sitting position and 6-Minute Walk Test (6MWT) from baseline (BL) to 78 weeks or patient's last study timepoint by ACE genotype. (A) Change in FVC (individual patient dot plot [left] and mean changes [right]). (B) Change in 6MWT (individual patient dot plot [left] and mean changes [right]). (C) Mean changes over time in patients treated with alglucosidase alfa. *P < 0.01 and **P < 0.05 compared to D/D alglucosidase alfa group according to ANOVA. Error bars represent standard deviation (SD).