Table 1. Baseline characteristics of trials (aggregate) versus DPP.
| DPP trial (lifestyle arm) | Included trials (IQR) | |
|---|---|---|
| Age (years) | 50.6 | 50.8 (49.0–56.4) |
| BMI | 33.7 | 34.8 (32.2–36.6) |
| Male (%) | 32.0 | 25.2% (15.0–31.3) |
| NHW (%) | 53.8 | 32.9% (0.0–86.0) |
| Weight (kg) | 93.5 | 99.3(91.5–101.7) |
| HbA1c (%) | 5.9 | 5.9 (5.7–6.0) |
| FBG (mg/dl) | 106.3 | 104.6 (99.0–107.6) |
| SBP (mm Hg) | 124 | 128.7 (123.5–133.6) |
| DBP (mm Hg) | 78 | 79.5 (77.2–82.5) |
| HDL (mg/dL) | 46.0 | 46.1 (44.7–49.7) |
| Total Cholesterol (mg/dL) | NR | 183.7 (183.0–192.1) |
| Screening method | Impaired fasting and elevated post-load glucose | Impaired fasting or elevated post load glucose or other high risk |
| Core lifestyle sessions offered | 16 | Mean 12.6 (Range 1–24, median 12.0) |
| Core lifestyle sessions attended | NR | Mean 11.0 (Range 3.67–25, median 10.1) |
| Type of sessions | 100% Individual | 16.7% individual, 70.8% group, 12.5% both |
| Setting | Clinical centers across US | Clinics, Community centers, Churches, Worksite, Internet |
| Duration of follow-up | Mean 2.8 y (Range 1–4 y) | Mean 9.3 mo, (Range 3–36, Median 12.0) |
| Maintenance | Yes (100%) | Sometimes (62.5%) |
| Delivery personnel | Mostly dieticians; also coaches with at least a master’s degree training in exercise physiology, behavioral psychology, or health education | Clinical personnel (physicians, nurses, dieticians, grad students) and nonclinical delivery (Internet-based classes and other lay community volunteers who underwent training) |
NR = not reported; BMI = body mass index; HbA1c = hemoglobin A1c; NHW = non-Hispanic white; SBP = systolic blood pressure; DBP = diastolic blood pressure; FBG = fasting blood glucose; HDL = high density lipoprotein cholesterol