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. Author manuscript; available in PMC: 2016 Jul 26.
Published in final edited form as: Curr Opin Chem Biol. 2015 Jun 5;28:20–28. doi: 10.1016/j.cbpa.2015.05.012

Figure 3.

Figure 3

Inducible inhibition of fatty acid elongation to enhance medium chain fatty acid production. In the system used in [63], fatty acid elongation was inhibited by an effector (purple circle) whose transcription was activated by exogenously added IPTG (red triangle). This slowed fatty acid synthesis and enhanced the production of the medium chain fatty acid, octanoate. Future systems could sense long chain fatty acids and avoid the need to add an exogenous inducer like IPTG.