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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Stroke. 2016 Jul 7;47(8):2103–2111. doi: 10.1161/STROKEAHA.116.012763

Figure 1.

Figure 1

Hsp70 reduces ischemic brain injury and improves neurological function. A, Representative cresyl violet-stained brain sections showed a smaller infarct in a Hsp transgenic brain (Hsp70Tg) compared to wildtype (Wt) and larger infarct in a Hsp knockout (Hsp70Ko). Infarct size among Hsp70Tg mice was reduced compared to Wt mice, and Hsp70Ko mice had larger infarcts. B, For 4 separate behavioral tests, Hsp70Ko mice performed worse than Wt and Hsp70Tg mice. Graphs show results from the Bederson, ladder, adhesive tape removal (time to remove tape from forelimbs), and elevated body swing tests (n=6–9/group, *P<0.01, **P<0.05).

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