Table 1.
Patient Characteristics and Univariable Analysis
| Variable | All patients | No 90-day mortality | 90-day mortality | p Value |
|---|---|---|---|---|
| Age, mean ± SD | 62.7 ± 11.1 | 61.9 ± 10.9 | 67.4 ± 10.6 | 0.003 |
| Sex | 0.05 | |||
| Female | 105 (36.6) | 96 (38.9) | 9 (22.5) | |
| Male | 182 (63.4) | 151 (61.1) | 31 (77.5) | |
| Bismuth classification | 0.14 | |||
| Left or right duct | 30 (10.5) | 29 (11.7) | 1 (2.5) | |
| 1 | 11 (3.8) | 11 (4.5) | 0 (0) | |
| 2 | 20 (7.0) | 17 (6.9) | 3 (7.5) | |
| 3A – right | 102 (35.5) | 82 (33.2) | 20 (50.0) | |
| 3B – left | 72 (25.1) | 61 (24.7) | 11 (27.5) | |
| 4 | 52 (18.1) | 47 (19.0) | 5 (12.5) | |
| Lobar atrophy | 0.63 | |||
| None | 172 (59.9) | 146 (59.1) | 26 (65.0) | |
| Right | 51 (17.8) | 46 (18.6) | 5 (12.5) | |
| Left | 64 (22.3) | 55 (22.3) | 9 (22.5) | |
| Type of liver resection | 0.79 | |||
| Central hepatectomy | 3 (1.0) | 3 (1.2) | 0 (0) | |
| Left hemihepatectomy | 102 (35.5) | 90 (36.4) | 12 (30.0) | |
| Left extended hemihepatectomy | 36 (12.5) | 31 (12.6) | 5 (12.5) | |
| Right hemihepatectomy | 46 (16.0) | 40 (16.2) | 6 (15.0) | |
| Right extended hemihepatectomy | 100 (34.8) | 83 (33.6) | 17 (42.5) | |
| Portal vein reconstruction | 0.11 | |||
| No | 236 (82.2) | 207 (83.8) | 29 (72.5) | |
| Yes | 51 (17.8) | 40 (16.2) | 11 (27.5) | |
| FLR volume* | 0.003 | |||
| Large >50% | 115 (47.3) | 105 (50.5) | 10 (28.6) | |
| Intermediate 30-50% | 76 (31.3) | 66 (31.7) | 10 (28.6) | |
| Small <30% | 52 (21.4) | 37 (17.8) | 15 (42.9) | |
| Jaundice | 0.009 | |||
| No | 46 (16.0) | 45 (18.2) | 1 (2.5) | |
| Yes | 241 (84.0) | 202 (81.8) | 39 (97.5) | |
| FLR drainage* | 0.28 | |||
| Complete | 173 (71.2) | 150 (72.1) | 23 (65.7) | |
| Incomplete | 70 (28.8) | 58 (27.9) | 12 (34.3) | |
| Incomplete drainage + FLR below 50%* | 0.04 | |||
| No | 204 (84.0) | 179 (86.1) | 25 (71.4) | |
| Yes | 39 (16.0) | 29 (13.9) | 10 (28.6) | |
| Preoperative cholangitis* | 0.001 | |||
| No | 213 (76.3) | 193 (79.8) | 20 (54.1) | |
| Yes | 66 (23.7) | 49 (20.2) | 17 (45.9) | |
| Hospital, n (%) | 0.04 | |||
| MSKCC | 151 (52.6) | 136 (55.1) | 15 (37.5) | |
| AMC | 136 (47.4) | 111 (44.9) | 25 (62.5) | |
| Resection margin† | 0.55 | |||
| R0 | 204 (75.6) | 176 (76.2) | 28 (71.8) | |
| R1 | 66 (24.4) | 55 (23.8) | 11 (28.2) |
Data are presented as number (%), unless stated otherwise.
*
The variable cholangitis was missing in 8 patients; FLR assessment was missing in 44 patients.
†
The variable resection margin excludes 17 patients with benign disease on final postoperative pathology.
FLR, future liver remnant; IQR interquartile range; SD, standard deviation