Table 1.

Mean Dice coefficient of the different subcortical structures over the 50 cases of template library.

Structure	volBrain	Freesurfer	FIRST
Lat. Ventricles	0.9836 ± 0.0111*	0.8315 ± 0.0589	—
Caudate	0.9427 ± 0.0196*†	0.8195 ± 0.0418	0.8366 ± 0.0706
Putamen	0.9442 ± 0.0226 *†	0.8162 ± 0.0396	0.8775 ± 0.0192
Thalamus	0.9476 ± 0.0196 *†	0.8157 ± 0.0247	0.8144 ± 0.0322
Pallidum	0.8914 ± 0.0403 *†	0.7454 ± 0.0906	0.7851 ± 0.0575
Hippocampus	0.9533 ± 0.0092 *†	0.7886 ± 0.0254	0.8429 ± 0.0303
Amygdala	0.8795 ± 0.0559 *†	0.5844 ± 0.1092	0.5895 ± 0.0962
Accumbens	0.8362 ± 0.0572 *†	0.5589 ± 0.0697	0.6483 ± 0.0916
Average	0.9224 ± 0.0570*†	0.7546 ± 0.1198	—
Average	0.9136 ± 0.0555 *†	0.7327 ± 0.1132	0.7706 ± 0.1087

Average represents the average dice without including lateral ventricles. Best results are in bold.

^*Indicates statistically significant differences between volBrain and Freesurfer (p < 0.05).

^†Indicates statistically significant differences between volBrain and FIRST.