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. 2016 Feb 1;11:515–534. doi: 10.1007/s11523-015-0411-8

Table 1.

List of selected drugs indicated in solid tumours

INN Brand name MA date Tumour type
Abiraterone acetate Zytiga® 05/09/2011 Prostate
Afatinib Giotrif® 25/09/2013 Lung
Aflibercept Zaltrap® 01/02/2013 Colorectal tract
Axitinib Inlyta® 03/09/2012 Kidney
Cabazitaxel Jevtana® 17/03/2011 Prostate
Cabozantinib Cometriq® 21/03/2014 Thyroid
Catumaxomab Removab® 20/04/2009 Ascites
Crizotinib Xalkori® 23/10/2012 Lung
Dabrafenib Tafinlar® 26/08/2013 Skin
Degarelix Firmagon® 17/02/2009 Prostate
Enzalutamide Xtandi® 21/06/2013 Prostate
Eribulin Halaven® 17/03/2011 Breast
Everolimus Afinitor® 03/08/2009 Breast, pancreas and kidney
Gefitinib Iressa® 24/06/2009 Lung
Ipilimumab Yervoy® 13/07/2011 Skin
Mifamurtide Mepact® 06/03/2009 Bones
Nintedanib Vargatef® 21/11/2014 Lung
Olaparib Lynparza® 16/12/2014 Ovaries, fallopian tubes and peritonea
Pazopanib Votrient® 14/06/2010 Kidney and soft-tissue
Pertuzumab Perjeta® 04/03/2013 Breast
Radium Ra223 dichloride Xofigo® 13/11/2013 Prostate
Ramucirumab Cyramza® 19/12/2014 Gastro-oesophageal tract
Regorafenib Stivarga® 26/08/2013 Colorectal tract
Sipuleucel-T Provenge® 06/09/2013 Prostate
Tegafur/Gimeracil/Oteracil Teysuno® 14/03/2011 Gastro-oesophageal tract
Trametinib Mekinist® 30/06/2014 Skin
Trastuzumab emtansine Kadcyla® 15/11/2013 Breast
Vandetanib Caprelsa® 17/02/2012 Thyroid
Vemurafenib Zelboraf® 17/02/2012 Skin
Vinflunine Javlor® 21/09/2009 Urothelial tract
Vismodegib Erivedge® 12/07/2013 Basal cells