Table 2.
The contribution of pro-inflammatory cytokines to the arthritis development in selected mouse models of arthritis
| Arthritis model | IL-17A | IL-6 | IL-1 | TNF | IL-23 | References |
|---|---|---|---|---|---|---|
| CIA | + | + | ++ | + | + | [53, 54] |
| AIA | + | + | NR | + | + | [59] |
| SCW-acute | - | + | + | + | + | [68] |
| SCW-flare | + | + | + | + | + | [69] |
| K/BxN | + | + | + | + | NR | [70] |
| K/BxN serum transfer | - | - | ++ | + | + | [60] |
| SKG | ++ | ++ | + | + | NR | [61] |
| Gp130 | NR | ++ | NR | NR | NR | [62] |
| IL-1Ra-/- | ++ | - | NR | ++ | NR | [63] |
| hTNF.tg | NR | - | ++ | ++ | NR | [64] |
| BXD2 | ++ | [65, 66] | ||||
| DNA II−/−IFN-IR−/− | + | + | + | + | NR | [67] |
NR not reported