Table 2.

CMV effect on CD56^dim NK cell responses and on CD56^bright/CD56^dim ratio.

Analyte	Stimulus	CMV	Mean	SEM	Sig.
CD107a	Nil	−	3.91	0.52	.808
		+	4.12	0.50
	K562	−	15.89	1.80	.937
		+	15.72	1.15
	NKp46	−	20.50	3.43	.755
		+	21.84	2.30
IFN-γ	Nil	−	1.31	0.24	.928
		+	1.34	0.20
	K562	−	3.46	0.64	.070
		+	2.32	0.30
	NKp46	−	9.33	1.47	.920
		+	9.11	1.23
	IL-2	−	2.00	0.37	.814
		+	2.12	0.28
	IL-15	−	2.63	0.48	.342
		+	3.94	0.83
	IL-12/18	−	20.55	4.67	.399
		+	16.54	2.32
MIP-1β	Nil	–	6.99	0.86	.048
		+	5.06	0.49
	K562	–	32.98	3.28	.599
		+	30.93	2.05
	NKp46	−	48.92	5.82	.725
		+	46.39	3.84
	IL-2	−	40.14	3.71	.123
		+	33.78	2.08
	IL-15	−	60.90	4.11	.450
		+	56.99	2.76
	IL-12/18	−	31.40	5.28	.420
		+	27.06	2.63
Ratio*	Nil	–	.0476	.0073	.960
		+	.0471	.0046

CD56^dim NK cells were gated and tested for the indicated analyte in response to the designated stimulus. Shown is the mean and standard error of the mean (SEM) for subjects who were CMV infected (+) or not CMV infected (−). Bold print denotes significant mean differences as determined by student׳s T test.

^*CD56^bright/CD56^dim ratio, tested immediately ex vivo.