Table 3.
Plasma TAS, TOS, OSI, protein carbonyls (PC), 4-HNE protein adduct, oxy-LDL/MDA, 8-isoprostanes (8-isoP), and 8-OHdG of the control and streptozotocin-diabetic rats.
TAS (μmol/mg of protein) M (min–max) |
TOS (μmol/mg of protein) M (min–max) |
OSI M (min–max) |
PC (pmol/mg of protein) M (min–max) |
4-HNE protein adduct (ng/mg of protein) M (min–max) |
oxy-LDL/MDA (pg/mg of protein) M (min–max) |
8-isoP (pg/mg of protein) M (min–max) |
8-OHdG (pg/mg of protein) M (min–max) |
|
---|---|---|---|---|---|---|---|---|
C1 | 0.1 (0.06–0.15) | 1.03 (0.32–2.44) | 1.03 (0.095–1.17) | 1.41 (1.07–1.48) | 0.004 (0.001–0.005) | 1.57 (0.99–2.64) | 0.0019 (0.0018–0.0022) | 0.20 (0.17–0.24) |
C2 | 0.1 (0.05–0.16) | 1.05 (0.88–1.28) | 0.7 (0.47–1.13) | 1.48 (1.31–2.01) | 0.005 (0.001–0.007) | 1.62 (1.47–2.24) | 0.0018 (0.0011–0.0023) | 0.21 (0.19–0.22) |
DM1 | 0.16 (0.09–0.20) | 2.84 (2.54–3.27) | 1.78 (1.57–2.51) | 1.57 (1.51–2.11) | 6.8 (6.7–7.5) | 2.29 (1.21–2.95) | 0.0023 (0.0019–0.0026) | 0.26 (0.24–0.30) |
DM2 | 0.077 (0.05–0.15) | 2.67 (2.48–2.74) | 1.31 (1.21–1.83) | 1.59 (1.09–2.19) | 6.5 (6.0–7.7) | 3.65 (3.08–4.01) | 0.0022 (0.0017–0.0026) | 0.26 (0.25–0.29) |
p (C1 : C2) | ns | ns | ns | ns | ns | ns | ns | ns |
p (DM1 : DM2) | ns | ns | ns | ns | ns | <0.005 (↑) | ns | ns |
p (C1 : DM1) | ns | <0.0005 (↑) | <0.005 (↑) | <0.05 (↑) | <0.00005 (↑) | <0.05 (↑) | <0.05 (↑) | ns |
p (C2 : DM2) | <0.05 (↓) | <0.0005 (↑) | <0.005 (↑) | <0.05 (↑) | <0.00005 (↑) | <0.005 (↑) | <0.05 (↑) | <0.05 (↑) |
C1: control group in the first week of the experiment, C2: control group in the second week of the experiment, DM1: diabetic group in the first week of the experiment, DM2: diabetic group in the first second of the experiment, TAS: total antioxidant status, TOS: total oxidant status, OSI: oxidative status index, PC: protein carbonyls, 4-HNE protein adduct: 4-hydroxynonenal protein adduct, oxy-LDL/MDA: oxidized and/or MDA-modified LDL-cholesterol, 8-isoP: 8-isoprostanes, 8-OHdG: 8-hydroxy-D-guanosine, ns: not significant, p: statistical significance < 0.05, M: median, min: minimum, max: maximum, (↓): decrease, and (↑): increase.