Table 3.
Frequency of abnormal sperm cells (Mean±Standard Error) induced in mice exposed to aqueous and hydro-methanol extracts of Spondias mombin, Nymphaea lotus and Lufffa cylindrica.
| Treatment | Mean ± SE | Mean ± SE | Mean ± SE | |
|---|---|---|---|---|
| Distilled water | 31.8±1.3 | 31.8±1.3 | 31.81.3 | |
| DMSO | 58.4±5.5† | 41.0±10.9† | 41.010.9† | |
| MMS | 83.8±26.7† | 83.8±26.7† | 83.826.7† | |
| Aqueous extracts | Conc. (mg/kg) | ASM | ANL | ALC |
| 200 | 88.6±32.8† | 85.3±40.8† | 41.7±15.0† | |
| 400 | 42.9±24.3† | 92.6±36.5† | 41.2±14.8† | |
| 800 | 45.0±19.6† | 66.9±28.7† | 50.2±17.1† | |
| 1600 | 31.3±23.7 | 27.4±26.2† | 48.7±16.2† | |
| Hydro-methanolic extracts | Conc. (mg/kg) | MSM | MNL | MLC |
| 50 | 26.2±2.0†‡ | 35.8±11.0†‡ | 23.8±6.7†‡ | |
| 100 | 39.6±1.9†‡ | 47.0±12.8†‡ | 33.6±8.8‡ | |
| 200 | 25.6±2.3†‡ | 48.0±19.5†‡ | 25.2±7.0†‡ | |
| 400 | 23.0±0.9†‡ | 76.8±33.5†‡ | 42.3±10.0‡ |
DMSO: dimethyl sulfoxide; MMS: methyl methane sulfonate, Conc: concentration; Significant difference from distilled water group
†
-(p<0.05); Significant difference from DMSO group
‡
-(p<0.05)