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. 2016 Jul 27;6:30377. doi: 10.1038/srep30377

Figure 6. Analysis of off-target knockdown.

Figure 6

(a) Scatter plot of expression level data from Acsl1 gapmer- and saline-administrated mice liver. (b) Presumptive off-target protein-coding genes of the Acsl1 gapmer which showed greater than two-fold significant change. qRT-PCR analysis of the gene expression in liver of gapmer- or GalNAc3-siRNA-treated mice (c), non-gapmer- or gapmer-treated mice (d), and si-RNaseH + gapmer (e) (n = 3 or 4, mean + S.D.).