Table 1. In Vitro Potency of Idelalisib on Human T-Cell Cytokine Production.

Cell Type	Stimuli (Receptor)	Assay	Readout	EC50(nM)
T cells	Anti-CD3/Anti-MHC II (TCR/MHC II)	Cytokines release	IL-4	2.4
			IL-5	2.7
			IL-13	3.1
			IL-17	3.5
			TNFα	5.2
			IFNγ	4.8
			IL-1β	6.1
			IL-12p70	2.3
			IL-10	2.6