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. 2016 Jul 26;4(14):e12852. doi: 10.14814/phy2.12852

Figure 6.

Figure 6

Quantification of power spectral data for the effects of quinine, Gap 26, and TMA on 4‐AP‐induced 4–12 Hz rhythmic activity in SG. (A) The attenuating effect of quinine on 4‐AP evoked activity, quantified as power amplitude and power area. Compared to ACSF alone, 4‐AP enhances activity. 4‐AP‐induced activity levels are diminished by quinine. (~P < 0.05, comparing 4‐AP to drug‐free ACSF; *P < 0.05, comparing 4‐AP plus quinine to 4‐AP alone for both amplitude and area). (B) Comparison of 4‐AP‐induced activity between control slices which were not preincubated in Gap 26 and spinal slices preincubated in Gap 26. Activity levels are diminished by Gap 26. (*P < 0.05, comparing 4‐AP plus Gap 26 to 4‐AP alone for both amplitude and area).