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. 2016 Jul 20;4(14):e12872. doi: 10.14814/phy2.12872

Table 2.

Timing of events at the level of the left ventricle and the common carotid artery

Event pairing Timing of events (% of heart cycle) Mean difference 95% CI P‐value ICC [95% CI] P‐value
CALM point Comparison event
CALM point A with
Onset of septal movement 3.30 ± 2.31 vs. 5.10 ± 2.47 −4.58 to 0.98 0.18 −0.32 [−0.77 to −0.35] 0.83
Apical prerotation peak 4.57 ± 1.99 vs. 1.00 ± 5.16 −7.08 to 2.22 0.25 0.17 [−0.61 to 0.78] 0.34
Basal prerotation peak 2.70 ± 3.57 vs. 12.90 ± 3.57 −14.13 to −6.27 <0.01 −0.50 [−0.85 to 0.15] 0.94
CALM point B with
Arrival of blood velocity wave 9.83 ± 3.03 vs. 10.73 ± 1.41 −2.19 to 0.39 0.17 −0.07 [−0.42 to 0.29] 0.65
Peak basal prerotation velocity 9.50 ± 3.31 vs. 7.60 ± 1.78 −0.83 to 4.63 0.15 −0.03 [−0.62 to 0.58] 0.54
CALM point C with
Peak blood velocity 18.57 ± 3.98 vs. 18.53 ± 2.81 0.80 to 0.86 0.94 0.79 [0.61 to 0.90] <0.01
Peak basal rotation velocity 18.30 ± 4.85 vs. 20.30 ± 4.69 −5.66 to 1.66 0.25 0.43 [−0.24 to 0.82] 0.10
CALM point D with
Peak septal displacement 42.60 ± 6.42 vs. 39.40 ± 5.72 −0.55 to 6.95 0.09 0.63 [0.04 to 0.89] 0.02
Peak apical rotation 41.00 ± 7.81 vs. 35.33 ± 5.79 2.23 to 9.10 <0.01 0.79 [0.31 to 0.95] <0.01
Peak basal rotation 41.80 ± 6.12 vs. 37.30 ± 5.66 1.44 to 7.56 <0.01 0.74 [0.24 to 0.93] <0.01

CALM, Carotid artery longitudinal motion; point A, onset of first deflection in the retrograde direction; point B, onset of first anterograde movement; point C, peak anterograde displacement; point D, peak retrograde displacement; 95% CI, 95% confidence interval. Bolded events are interpreted as occurring at a similar time. Values are means ± SD.

CALM points differ slightly in timing as analysis of data was performed on simultaneously collected heart cycles when possible.